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Over the counter Published: human trials Established use

Vitamin K2 (MK-7): dosing, timing and what to expect

Directs calcium into bone rather than arterial wall. Mostly taken as insurance alongside vitamin D, whose whole job is increasing calcium absorption.

Also known as menaquinone, MK-7

Educational research reference Supplements
Quick reference. Everything you need to run Vitamin K2 (MK-7) — dosing, frequency, reconstitution math for the vial sizes people actually buy, and what it stacks with. For anything specific to your situation, ask the Guru.

Vitamin K2 (MK-7) quick start

Route
Oral
Typical dose
100–200 mcg daily
Frequency
Daily
Half-life
MK-7 lasts around three days, which is why it is preferred over MK-4.
Cycle
Continuous alongside D3.
These are the numbers people actually run, drawn from the published record and from what the community has settled on over time. Educational reference, not medical advice — a starting point to work from, and one you can adjust as you learn how you respond.

How to run it

How often
Daily
Cycle length
Continuous alongside D3.
Half-life
MK-7 lasts around three days, which is why it is preferred over MK-4.
Route
Oral
Consistency matters more than perfect timing. Pick a slot in your day you will actually keep, and let DoseIQ handle the rest.

What to expect

Most people tolerate Vitamin K2 (MK-7) well. Here is what is worth knowing going in, so nothing catches you by surprise.

The one hard contraindication on this list: if you take warfarin, K2 directly opposes it. Talk to whoever manages your anticoagulation before starting, not after. Otherwise very well tolerated.

Known interactions

Interactions involving Vitamin K2 (MK-7)'s drug class that DoseIQ screens for. Each one cites where it comes from — an FDA label section or the published record — because an interaction warning you can't trace is just noise.

Serious Vitamin K2 + warfarin — directly opposed

Warfarin works by blocking vitamin K; supplementing K2 pushes the other way and destabilizes INR.

What to do: Don't start, stop, or change K2 without the prescriber managing your warfarin — consistency matters more than abstinence.

Source: FDA label, warfarin §7; standard anticoagulation practice

DoseIQ screens your whole protocol against these rules automatically — every compound, prescription and supplement you track, cross-checked as you add them. Serious flags are always free.

Preparing it

Vitamin K2 (MK-7) does not need reconstituting — it comes ready to use.
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This page is an educational research reference and is not medical advice. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.