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Research chemical Published: limited Emerging use

Thymalin: dosing, reconstitution and evidence

A thymus-derived peptide complex from the same Russian research tradition as Epitalon, used for immune restoration in older adults.

Also known as Thymus peptide extract

Educational research reference Immune
Quick reference. Everything you need to run Thymalin — dosing, frequency, reconstitution math for the vial sizes people actually buy, and what it stacks with. For anything specific to your situation, ask the Guru.

Thymalin quick start

Route
SubQ or IM
Typical dose
5–10 mg
Frequency
Daily for 10 days
Half-life
Not established.
Cycle
10 day courses, 2× per year.
Vial sizes sold
10mg or 20mg
These are the numbers people actually run, drawn from the published record and from what the community has settled on over time. Educational reference, not medical advice — a starting point to work from, and one you can adjust as you learn how you respond.

How to run it

How often
Daily for 10 days
Cycle length
10 day courses, 2× per year.
Half-life
Not established.
Route
SubQ or IM
Consistency matters more than perfect timing. Pick a slot in your day you will actually keep, and let DoseIQ handle the rest.

What to expect

Most people tolerate Thymalin well. Here is what is worth knowing going in, so nothing catches you by surprise.

Evidence is limited to Russian-language studies that have not been independently replicated. A peptide complex rather than a single defined molecule, so composition varies by source.

Reconstitution guide

Thymalin ships as a lyophilised powder and gets mixed with bacteriostatic water before use. How much water you add sets the concentration, which sets how many syringe units make up each dose. One unit on a U-100 syringe is 0.01 mL — the tables below do the arithmetic for the vial sizes you are most likely to be holding.

10mg vial most common

Water addedConcentration 5mg10mg
2mL (common) 5 mg/mL1.00 mL
100 units		2.00 mL
200 units *
3mL 3.33 mg/mL1.50 mL
150 units *		3.00 mL
300 units *

20mg vial

Water addedConcentration 5mg10mg
2mL (common) 10 mg/mL0.50 mL
50 units		1.00 mL
100 units
3mL 6.67 mg/mL0.75 mL
75 units		1.50 mL
150 units *

* More than 100 units — that is more than a single U-100 insulin syringe holds. Either use a larger syringe, split it across two draws, or mix with less water to concentrate it. Adding less water is usually the easier fix.

10 mg vial + 1 mL BAC water = 10 mg/mL — a 5 mg dose = 50 units on a U-100 syringe. 20 mg vial + 2 mL = 10 mg/mL — 5 mg = 50 units.

Standard steps

  1. Inspect the vialConfirm the label and that the powder cake is intact. Do not use a cracked or compromised vial.
  2. Let it reach room temperatureSitting out for a few minutes reduces condensation inside the vial when the seal is broken.
  3. Disinfect both stoppersWipe the compound vial and the bacteriostatic water vial with a fresh alcohol swab and let them air-dry.
  4. Draw the bacteriostatic waterUse a sterile syringe to draw the volume you have chosen from the reconstitution table.
  5. Add the water down the vial wallInject slowly so it runs down the inside wall rather than spraying directly onto the powder. This limits foaming.
  6. Dissolve gentlySwirl or roll the vial between your hands until the cake dissolves. Never shake — agitation damages peptide bonds. The solution should end up clear.
  7. Label and refrigerateWrite the reconstitution date and concentration on the vial. Store at 2–8°C. Do not freeze.
Running a different vial size or water volume? The DoseIQ calculator works it out for any combination — mcg, mg or IU, on any syringe size.
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This page is an educational research reference and is not medical advice. Thymalin is not approved for human use in any jurisdiction. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.