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Research chemical Published: limited Established use

Semax / Selank Blend: dosing, reconstitution and evidence

Two Russian-developed peptides in one vial. Semax is stimulating and pro-focus; Selank is anxiolytic and calming. Together they are used for focus without the wired feeling Semax alone can produce.

Also known as Selank Semax, Semax+Selank, nootropic blend

Educational research reference Blends & Stacks
Quick reference. Everything you need to run Semax / Selank Blend — dosing, frequency, reconstitution math for the vial sizes people actually buy, and what it stacks with. For anything specific to your situation, ask the Guru.

Semax / Selank Blend quick start

Route
SubQ, or intranasal
Typical dose
600–1,200 mcg total blend per dose — usually an even split, but confirm on your label
Frequency
Once or twice daily
Half-life
Both are short-acting — minutes to a few hours — which is why dosing is daily and effects are felt acutely.
Cycle
2–4 weeks on, then a break. Tolerance to the focus effect builds.
Vial sizes sold
20mg or 30mg
These are the numbers people actually run, drawn from the published record and from what the community has settled on over time. Educational reference, not medical advice — a starting point to work from, and one you can adjust as you learn how you respond.

How to run it

How often
Once or twice daily
Cycle length
2–4 weeks on, then a break. Tolerance to the focus effect builds.
Half-life
Both are short-acting — minutes to a few hours — which is why dosing is daily and effects are felt acutely.
Route
SubQ, or intranasal
Consistency matters more than perfect timing. Pick a slot in your day you will actually keep, and let DoseIQ handle the rest.

What people actually run

Paired because they pull in different directions — Semax for drive and focus, Selank for taking the edge off it. The combination is more popular than either alone.

This is accumulated community practice — years of real-world use across a large number of people, converging on numbers that work. It is not a controlled trial, and for most compounds here no such trial exists or is ever likely to. That makes this the most reliable dosing signal available, and it is a good deal better than guessing.

What to expect

Most people tolerate Semax / Selank Blend well. Here is what is worth knowing going in, so nothing catches you by surprise.

Well tolerated, and the pairing exists specifically to soften Semax's stimulation. Effects are subtle and subjective — nobody should expect a stimulant. Neither has Western regulatory approval, and the human research is almost entirely Russian and hard to verify independently.

Reconstitution guide

Semax / Selank Blend ships as a lyophilised powder and gets mixed with bacteriostatic water before use. How much water you add sets the concentration, which sets how many syringe units make up each dose. One unit on a U-100 syringe is 0.01 mL — the tables below do the arithmetic for the vial sizes you are most likely to be holding.

20mg vial most common

Water addedConcentration 600mcg1200mcg
2mL (common) 10 mg/mL0.06 mL
6 units		0.12 mL
12 units
3mL 6.67 mg/mL0.09 mL
9 units		0.18 mL
18 units

30mg vial

Water addedConcentration 600mcg1200mcg
2mL (common) 15 mg/mL0.04 mL
4 units		0.08 mL
8 units
3mL 10 mg/mL0.06 mL
6 units		0.12 mL
12 units
Commonly sold as a combined milligram figure. Intranasal use needs a much smaller volume than injection, so mix accordingly.

Standard steps

  1. Inspect the vialConfirm the label and that the powder cake is intact. Do not use a cracked or compromised vial.
  2. Let it reach room temperatureSitting out for a few minutes reduces condensation inside the vial when the seal is broken.
  3. Disinfect both stoppersWipe the compound vial and the bacteriostatic water vial with a fresh alcohol swab and let them air-dry.
  4. Draw the bacteriostatic waterUse a sterile syringe to draw the volume you have chosen from the reconstitution table.
  5. Add the water down the vial wallInject slowly so it runs down the inside wall rather than spraying directly onto the powder. This limits foaming.
  6. Dissolve gentlySwirl or roll the vial between your hands until the cake dissolves. Never shake — agitation damages peptide bonds. The solution should end up clear.
  7. Label and refrigerateWrite the reconstitution date and concentration on the vial. Store at 2–8°C. Do not freeze.
Running a different vial size or water volume? The DoseIQ calculator works it out for any combination — mcg, mg or IU, on any syringe size.
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This page is an educational research reference and is not medical advice. Semax / Selank Blend is not approved for human use in any jurisdiction. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.