Selank: dosing, reconstitution and evidence
A synthetic tuftsin analog, also Russian-developed, used as an anxiolytic. Modulates GABA and serotonin without the sedation or dependence associated with benzodiazepines.
Also known as Tuftsin analog, TP-7
Selank quick start
- Route
- SubQ, or intranasal
- Typical dose
- 250–500 mcg
- Frequency
- 1–2× daily
- Half-life
- Short — minutes in plasma.
- Cycle
- 2–4 week courses.
- Vial sizes sold
- 10mg or 5mg
How to run it
- How often
- 1–2× daily
- Cycle length
- 2–4 week courses.
- Half-life
- Short — minutes in plasma.
- Route
- SubQ, or intranasal
What people actually run
The anxiolytic half of the Semax/Selank pair. Steady, long-running community use.
What to expect
Most people tolerate Selank well. Here is what is worth knowing going in, so nothing catches you by surprise.
Reconstitution guide
Selank ships as a lyophilised powder and gets mixed with bacteriostatic water before use. How much water you add sets the concentration, which sets how many syringe units make up each dose. One unit on a U-100 syringe is 0.01 mL — the tables below do the arithmetic for the vial sizes you are most likely to be holding.
10mg vial most common
| Water added | Concentration | 250mcg | 500mcg |
|---|---|---|---|
| 2mL (common) | 5 mg/mL | 0.05 mL 5 units | 0.10 mL 10 units |
| 3mL | 3.33 mg/mL | 0.07 mL 7.5 units | 0.15 mL 15 units |
5mg vial
| Water added | Concentration | 250mcg | 500mcg |
|---|---|---|---|
| 2mL (common) | 2.5 mg/mL | 0.10 mL 10 units | 0.20 mL 20 units |
| 3mL | 1.67 mg/mL | 0.15 mL 15 units | 0.30 mL 30 units |
Standard steps
- Inspect the vialConfirm the label and that the powder cake is intact. Do not use a cracked or compromised vial.
- Let it reach room temperatureSitting out for a few minutes reduces condensation inside the vial when the seal is broken.
- Disinfect both stoppersWipe the compound vial and the bacteriostatic water vial with a fresh alcohol swab and let them air-dry.
- Draw the bacteriostatic waterUse a sterile syringe to draw the volume you have chosen from the reconstitution table.
- Add the water down the vial wallInject slowly so it runs down the inside wall rather than spraying directly onto the powder. This limits foaming.
- Dissolve gentlySwirl or roll the vial between your hands until the cake dissolves. Never shake — agitation damages peptide bonds. The solution should end up clear.
- Label and refrigerateWrite the reconstitution date and concentration on the vial. Store at 2–8°C. Do not freeze.
This page is an educational research reference and is not medical advice. Selank is not approved for human use in any jurisdiction. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.