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Over the counter Published: RCT evidence Extensive real-world use

Omega-3 (EPA/DHA): dosing, timing and what to expect

Long-chain fatty acids with well-established cardiovascular and anti-inflammatory effects. Relevant on TRT because testosterone raises haematocrit, and relevant to fertility because DHA is a major component of the sperm membrane.

Also known as fish oil, EPA, DHA

Educational research reference Supplements
Quick reference. Everything you need to run Omega-3 (EPA/DHA) — dosing, frequency, reconstitution math for the vial sizes people actually buy, and what it stacks with. For anything specific to your situation, ask the Guru.

Omega-3 (EPA/DHA) quick start

Route
Oral
Typical dose
2–3 g combined EPA/DHA daily
Frequency
Daily
Half-life
Incorporates into membranes over weeks.
Cycle
Continuous.
These are the numbers people actually run, drawn from the published record and from what the community has settled on over time. Educational reference, not medical advice — a starting point to work from, and one you can adjust as you learn how you respond.

How to run it

How often
Daily
Cycle length
Continuous.
Half-life
Incorporates into membranes over weeks.
Route
Oral
Consistency matters more than perfect timing. Pick a slot in your day you will actually keep, and let DoseIQ handle the rest.

What people actually run

Worth taking specifically on TRT, where haematocrit rises and blood viscosity is the thing you are managing.

This is accumulated community practice — years of real-world use across a large number of people, converging on numbers that work. It is not a controlled trial, and for most compounds here no such trial exists or is ever likely to. That makes this the most reliable dosing signal available, and it is a good deal better than guessing.

What to expect

Most people tolerate Omega-3 (EPA/DHA) well. Here is what is worth knowing going in, so nothing catches you by surprise.

Mildly antiplatelet, so it compounds with aspirin, warfarin or anything else thinning your blood — worth mentioning to whoever is managing that. Buy on EPA/DHA content rather than capsule size; "1000 mg fish oil" is often 300 mg of what you actually want. Rancid fish oil is common and actively pro-inflammatory, so buy fresh and refrigerate.

Preparing it

Omega-3 (EPA/DHA) does not need reconstituting — it comes ready to use.
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This page is an educational research reference and is not medical advice. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.