Research chemical Published: animal data only Emerging use

Follistatin-344: dosing, reconstitution and evidence

A myostatin-inhibiting glycoprotein. Myostatin limits muscle growth, so blocking it produces dramatic hypertrophy in animal models.

Also known as FS-344

Educational research reference Growth Hormone

Quick reference. Everything you need to run Follistatin-344 — dosing, frequency, reconstitution math for the vial sizes people actually buy, and what it stacks with. For anything specific to your situation, ask the Guru.

Follistatin-344 quick start

Route: SubQ
Typical dose: 100 mcg
Frequency: Daily for 10–30 days
Half-life: Not established in humans; native follistatin clears within hours.
Cycle: 10–30 day courses.
Vial sizes sold: 1mg

These are the numbers people actually run, drawn from the published record and from what the community has settled on over time. Educational reference, not medical advice — a starting point to work from, and one you can adjust as you learn how you respond.

How to run it

How often: Daily for 10–30 days
Cycle length: 10–30 day courses.
Half-life: Not established in humans; native follistatin clears within hours.
Route: SubQ

Consistency matters more than perfect timing. Pick a slot in your day you will actually keep, and let DoseIQ handle the rest.

What people actually run

Limited use — expensive, frequently counterfeit, and the least characterised item in the library.

This is accumulated community practice — years of real-world use across a large number of people, converging on numbers that work. It is not a controlled trial, and for most compounds here no such trial exists or is ever likely to. That makes this the most reliable dosing signal available, and it is a good deal better than guessing.

What to expect

Most people tolerate Follistatin-344 well. Here is what is worth knowing going in, so nothing catches you by surprise.

Two practical problems before any biological ones: it is expensive, and the counterfeit rate is high, so sourcing and third-party testing matter more here than almost anywhere else in this library. Myostatin inhibition also acts on cardiac muscle, and the long-term picture there is genuinely not mapped out. Most people get better value from better-characterised options first.

Reconstitution guide

Follistatin-344 ships as a lyophilised powder and gets mixed with bacteriostatic water before use. How much water you add sets the concentration, which sets how many syringe units make up each dose. One unit on a U-100 syringe is 0.01 mL — the tables below do the arithmetic for the vial sizes you are most likely to be holding.

1mg vial most common

Water added	Concentration	100mcg
1mL (common)	1 mg/mL	0.10 mL 10 units
2mL	500 mcg/mL	0.20 mL 20 units

1 mg vial + 1 mL BAC water = 1 mg/mL — a 100 mcg dose = 10 units on a U-100 syringe.

Standard steps

Inspect the vialConfirm the label and that the powder cake is intact. Do not use a cracked or compromised vial.
Let it reach room temperatureSitting out for a few minutes reduces condensation inside the vial when the seal is broken.
Disinfect both stoppersWipe the compound vial and the bacteriostatic water vial with a fresh alcohol swab and let them air-dry.
Draw the bacteriostatic waterUse a sterile syringe to draw the volume you have chosen from the reconstitution table.
Add the water down the vial wallInject slowly so it runs down the inside wall rather than spraying directly onto the powder. This limits foaming.
Dissolve gentlySwirl or roll the vial between your hands until the cake dissolves. Never shake — agitation damages peptide bonds. The solution should end up clear.
Label and refrigerateWrite the reconstitution date and concentration on the vial. Store at 2–8°C. Do not freeze.

Running a different vial size or water volume? The DoseIQ calculator works it out for any combination — mcg, mg or IU, on any syringe size.

Track this in DoseIQ Browse all compounds

This page is an educational research reference and is not medical advice. Follistatin-344 is not approved for human use in any jurisdiction. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.