All compounds
Research chemical Published: animal data only Extensive real-world use

BPC-157 / TB-500 Blend: dosing, reconstitution and evidence

The two best-known recovery peptides in one vial. BPC-157 works locally on tendon, ligament and gut tissue; TB-500 works systemically on cell migration. They are run together so often that vendors simply pre-mixed them.

Also known as Wolverine blend, Wolverine stack, BPC/TB, BPC-157 TB-500

Educational research reference Blends & Stacks
Quick reference. Everything you need to run BPC-157 / TB-500 Blend — dosing, frequency, reconstitution math for the vial sizes people actually buy, and what it stacks with. For anything specific to your situation, ask the Guru.

BPC-157 / TB-500 Blend quick start

Route
SubQ
Typical dose
500–1,000 mcg total blend per dose — usually an even split, but confirm on your label
Frequency
Once daily, or 2x weekly for loading
Half-life
BPC-157 is short and dosed daily; TB-500 is long and often dosed twice weekly. The blend forces both onto one schedule.
Cycle
4–8 weeks, then off.
Vial sizes sold
20mg or 10mg
These are the numbers people actually run, drawn from the published record and from what the community has settled on over time. Educational reference, not medical advice — a starting point to work from, and one you can adjust as you learn how you respond.

How to run it

How often
Once daily, or 2x weekly for loading
Cycle length
4–8 weeks, then off.
Half-life
BPC-157 is short and dosed daily; TB-500 is long and often dosed twice weekly. The blend forces both onto one schedule.
Route
SubQ
Consistency matters more than perfect timing. Pick a slot in your day you will actually keep, and let DoseIQ handle the rest.

What people actually run

The single most-run blend in the recovery space, and the reason most people buy a blend at all. Usually a 1:1 split, most often 10 mg of each in a 20 mg vial.

This is accumulated community practice — years of real-world use across a large number of people, converging on numbers that work. It is not a controlled trial, and for most compounds here no such trial exists or is ever likely to. That makes this the most reliable dosing signal available, and it is a good deal better than guessing.

What to expect

Most people tolerate BPC-157 / TB-500 Blend well. Here is what is worth knowing going in, so nothing catches you by surprise.

The real trade-off is scheduling: BPC-157 suits daily dosing and TB-500 has a much longer half-life, so a blend compromises one or the other. Most people accept that for the convenience. Both are angiogenic, so the same malignancy conversation applies as for either alone, and both are on the WADA Prohibited List.

Reconstitution guide

BPC-157 / TB-500 Blend ships as a lyophilised powder and gets mixed with bacteriostatic water before use. How much water you add sets the concentration, which sets how many syringe units make up each dose. One unit on a U-100 syringe is 0.01 mL — the tables below do the arithmetic for the vial sizes you are most likely to be holding.

20mg vial most common

Water addedConcentration 500mcg1000mcg
2mL (common) 10 mg/mL0.05 mL
5 units		0.10 mL
10 units
3mL 6.67 mg/mL0.07 mL
7.5 units		0.15 mL
15 units

10mg vial

Water addedConcentration 500mcg1000mcg
2mL (common) 5 mg/mL0.10 mL
10 units		0.20 mL
20 units
3mL 3.33 mg/mL0.15 mL
15 units		0.30 mL
30 units
Check whether your vial states the TOTAL milligrams or the amount of EACH peptide. A "20 mg" blend is usually 10 mg of each, but that is a convention rather than a rule.

Standard steps

  1. Inspect the vialConfirm the label and that the powder cake is intact. Do not use a cracked or compromised vial.
  2. Let it reach room temperatureSitting out for a few minutes reduces condensation inside the vial when the seal is broken.
  3. Disinfect both stoppersWipe the compound vial and the bacteriostatic water vial with a fresh alcohol swab and let them air-dry.
  4. Draw the bacteriostatic waterUse a sterile syringe to draw the volume you have chosen from the reconstitution table.
  5. Add the water down the vial wallInject slowly so it runs down the inside wall rather than spraying directly onto the powder. This limits foaming.
  6. Dissolve gentlySwirl or roll the vial between your hands until the cake dissolves. Never shake — agitation damages peptide bonds. The solution should end up clear.
  7. Label and refrigerateWrite the reconstitution date and concentration on the vial. Store at 2–8°C. Do not freeze.
Running a different vial size or water volume? The DoseIQ calculator works it out for any combination — mcg, mg or IU, on any syringe size.
Track this in DoseIQ Browse all compounds

This page is an educational research reference and is not medical advice. BPC-157 / TB-500 Blend is not approved for human use in any jurisdiction. Dose figures reflect the published record and what the community has converged on — starting points to weigh, not instructions. Consult a qualified healthcare provider before starting any protocol.